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Alexander T Cohen Selected Research

betrixaban

6/2020Budget impact analysis of betrixaban for venous thromboembolism prophylaxis in nonsurgical patients with acute medical illness in the United Kingdom.
2/2020Extended prophylaxis of venous thromboembolism with betrixaban in acutely ill medical patients with and without cancer: insights from the APEX trial.
12/2019Net-clinical benefit of extended prophylaxis of venous thromboembolism with betrixaban in medically ill patients aged 80 or more.
10/2019Effectiveness and safety of betrixaban extended prophylaxis for venous thromboembolism compared with standard-duration prophylaxis intervention in acute medically ill patients: a systematic literature review and network meta-analysis.
4/2019Characterization of Major and Clinically Relevant Non-Major Bleeds in the APEX Trial.
1/2019Cost-Effectiveness of Betrixaban Compared with Enoxaparin for Venous Thromboembolism Prophylaxis in Nonsurgical Patients with Acute Medical Illness in the United States.
1/2019Extended-duration betrixaban versus shorter-duration enoxaparin for venous thromboembolism prophylaxis in critically ill medical patients: an APEX trial substudy.
1/2018Symptomatic event reduction with extended-duration betrixaban in acute medically ill hospitalized patients.
1/2018Increased benefit of betrixaban among patients with a history of venous thromboembolism: a post-hoc analysis of the APEX trial.
1/2018Extended-Duration Betrixaban Reduces the Risk of Rehospitalization Associated With Venous Thromboembolism Among Acutely Ill Hospitalized Medical Patients: Findings From the APEX Trial (Acute Medically Ill Venous Thromboembolism Prevention With Extended Duration Betrixaban Trial).
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Alexander T Cohen Research Topics

Disease

101Venous Thromboembolism
10/2022 - 03/2002
73Hemorrhage
10/2022 - 08/2004
30Venous Thrombosis (Deep-Vein Thrombosis)
01/2022 - 11/2002
27Pulmonary Embolism
01/2022 - 01/2005
26Neoplasms (Cancer)
01/2022 - 03/2002
17Thrombosis (Thrombus)
01/2022 - 03/2002
9Stroke (Strokes)
01/2020 - 03/2009
5Body Weight (Weight, Body)
08/2021 - 09/2016
4Obesity
08/2021 - 02/2005
4Atrial Fibrillation
02/2021 - 01/2018
4Thromboembolism
11/2016 - 01/2005
3Heart Failure
11/2017 - 06/2003
3Myocardial Infarction
05/2014 - 07/2009
2Embolism (Embolus)
10/2022 - 05/2015
2Renal Insufficiency (Renal Failure)
01/2019 - 03/2017
2Inflammation (Inflammations)
01/2019 - 01/2017
2Ischemic Stroke
01/2017 - 05/2014
2Varicose Veins (Varicose Vein)
04/2016 - 02/2005
2Infections
04/2012 - 06/2003
2Peripheral Vascular Diseases (Peripheral Vascular Disease)
02/2010 - 07/2009
1Chronic Renal Insufficiency
06/2022
1Chronic Kidney Failure (Chronic Renal Failure)
06/2022
1Phlebitis
01/2022
1Hepatic Veno-Occlusive Disease (Disease, Hepatic Veno-Occlusive)
01/2022
1Hepatic Infarction
01/2022
1Budd-Chiari Syndrome (Budd Chiari Syndrome)
01/2022
1Thrombocytopenia (Thrombopenia)
08/2021
1Idiopathic Thrombocytopenic Purpura (Thrombocytopenic Purpura, Autoimmune)
08/2021
1Thrombotic Microangiopathies
08/2021
1Gastrointestinal Neoplasms (Gastrointestinal Cancer)
06/2021
1Hematoma
01/2021
1Cerebral Hemorrhage
01/2021
1Lung Diseases (Lung Disease)
01/2020
1Liver Diseases (Liver Disease)
01/2020
1Wounds and Injuries (Trauma)
01/2020
1Dementia (Dementias)
01/2020
1Cardiovascular Diseases (Cardiovascular Disease)
01/2019
1Critical Illness (Critically Ill)
01/2019
1Intracranial Hemorrhages (Intracranial Hemorrhage)
01/2019
1Frailty
11/2018
1Multiple Myeloma
10/2018
1Chronic Disease (Chronic Diseases)
01/2018
1Nausea
01/2018

Drug/Important Bio-Agent (IBA)

46AnticoagulantsIBA
06/2022 - 01/2006
35Enoxaparin (Lovenox)FDA LinkGeneric
10/2022 - 03/2002
25RivaroxabanIBA
10/2022 - 06/2012
25apixabanIBA
06/2022 - 02/2014
24Warfarin (Coumadin)FDA LinkGeneric
06/2022 - 11/2002
22Low-Molecular-Weight Heparin (Heparin, Low Molecular Weight)IBA
01/2022 - 11/2002
20betrixabanIBA
06/2020 - 03/2014
19Vitamin KFDA Link
07/2020 - 07/2010
15edoxabanIBA
01/2022 - 09/2010
13Heparin (Liquaemin)FDA LinkGeneric
01/2018 - 02/2008
9fibrin fragment D (D-dimer)IBA
01/2019 - 05/2004
7Pharmaceutical PreparationsIBA
10/2022 - 09/2013
7Aspirin (Acetylsalicylic Acid)FDA LinkGeneric
11/2020 - 01/2006
7Factor Xa InhibitorsIBA
01/2019 - 01/2016
5Dalteparin (Dalteparin Sodium)FDA Link
01/2022 - 08/2004
5DabigatranFDA Link
07/2020 - 06/2012
5Fondaparinux (Arixtra)FDA Link
06/2020 - 02/2006
4Factor Xa (Coagulation Factor Xa)IBA
01/2019 - 01/2016
3PRT064445IBA
04/2022 - 01/2016
3Biomarkers (Surrogate Marker)IBA
01/2019 - 01/2015
3Member 1 Subfamily B ATP Binding Cassette TransporterIBA
01/2019 - 09/2016
3ORALIT (ORS)IBA
01/2018 - 10/2017
3pro-brain natriuretic peptide (1-76)IBA
01/2018 - 09/2016
3Brain Natriuretic Peptide (Natrecor)FDA Link
11/2017 - 09/2016
3melagatranIBA
01/2006 - 02/2003
3ximelagatran (Exanta)IBA
01/2006 - 02/2003
2CreatinineIBA
07/2020 - 09/2016
2C-Reactive ProteinIBA
01/2019 - 11/2017
2A-factor (Streptomyces)IBA
01/2019 - 01/2016
2cupric sulfide (CuS)IBA
12/2018 - 01/2018
2AntithrombinsIBA
01/2006 - 02/2003
2enoxaparin sodiumFDA LinkGeneric
01/2005 - 05/2004
1Prothrombin (Factor II)IBA
04/2022
12- methyl- 3- (4- phenylpiperidino)propionohydroxamic acid hydrochloride (K 76)IBA
01/2022
1COVID-19 VaccinesIBA
08/2021
1VaccinesIBA
08/2021
1Antineoplastic Agents (Antineoplastics)IBA
05/2020
1Hemostatics (Antihemorrhagics)IBA
01/2019
1Serum AlbuminIBA
01/2019
1Antihypertensive Agents (Antihypertensives)IBA
01/2019
1AlbuminsIBA
01/2019
1Immunomodulating AgentsIBA
10/2018
1AntiemeticsIBA
01/2018
1hemoglobin ASIBA
01/2018

Therapy/Procedure

35Therapeutics
04/2022 - 07/2010
6Secondary Prevention
12/2019 - 03/2009
4Drug Therapy (Chemotherapy)
06/2021 - 02/2011
4Hip Replacement Arthroplasty (Total Hip Replacement)
09/2010 - 11/2002
2Bridge Therapy
01/2020 - 11/2018
2Operative Surgical Procedures
01/2020 - 02/2011
2Length of Stay
01/2016 - 12/2015
2Orthopedic Procedures
01/2006 - 11/2002
1Catheters
12/2021
1Oral Administration
02/2021
1Anticoagulation Reversal
01/2021
1Time-to-Treatment
01/2021
1Polypharmacy
01/2018